Josefina Castex

PhD Student

University Freiburg Medical Centre
Department of Urology, Centre for Clinical Research

2017 PhD thesis, Albert-Ludwigs-University of Freiburg
2014 - 2017 PhD student in the Lab of Prof. Dr. Roland Schüle, Centre for Clinical Research, University Freiburg Medical Centre
2011 - 2013 Master in Dental Sc. – Master in Biomedical Sc., KU Leuven, Belgium
2005 - 2010 Bachelor in Dental Sc., Los Andes University, Chile


  • Castex J., Willmann D., Kanouni T., Arrigoni L., Li Y., Friedrich M., Schleicher M., Wohrle S., Pearson M., Kraut N., Meret M., Manke T., Metzger E., Schule R. and Gunther T. (2017) Inactivation of Lsd1 triggers senescence in trophoblast stem cells by induction of Sirt4. Cell Death Dis 8, e2631.
  • Fedorov O., Castex J., Tallant C., Owen D.R., Martin S., Aldeghi M., Monteiro O., Filippakopoulos P., Picaud S., Trzupek J.D., Gerstenberger B.S., Bountra C., Willmann D., Wells C., Philpott M., Rogers C., Biggin P.C., Brennan P.E., Bunnage M.E., Schule R., Gunther T., Knapp S. and Muller S. (2015) Selective targeting of the BRG/PB1 bromodomains impairs embryonic and trophoblast stem cell maintenance. Sci Adv 1, e1500723.