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A04

Eva-Maria Herrlinger

2010 - 2013 Studies of Pharmaceutical Sciences (B.Sc.) at the University of Freiburg
2013 Bachelor of Science
2013 - 2015 Studies of Pharmaceutical Sciences (M.Sc.) at the University of Freiburg
2015 Master of Science
2016 - present PhD student in the Lab of Prof. Dr. Manfred Jung, Institute of Pharmaceutical Sciences (Medicinal Chemistry), Albert-Ludwigs-University of Freiburg
2017

Mirjam Julia Hau

2008 - 2012 Studies of Applied Chemistry (B.Sc.) at the Reutlingen University
2012 Bachelor of Science in Applied Chemistry
2011 - 2012 Internship and Bachelor Thesis at the Karlsruhe Institute of Technology (KIT)
2012 - 2015 Studies of Chemistry (M.Sc.) at the University of Freiburg
2015 Master of Science in Chemistry
2015 - present

Martin Roatsch

2006 - 2009 Studies of Chemistry (B.Sc.), University of Leipzig
2009 Bachelor of Science (summa cum laude)
2009 - 2011 Studies of Chemistry (M.Sc.), University of Leipzig
2010 Erasmus Semester at École Nationale Supérieure de Chimie de Montpellier (ENSCM), Montpellier, France
2011 Master of Science (summa cum laude)
2012 - 2016

Inga Hoffmann

2006 - 2010 Study of Pharmacy, Albert-Ludwigs-University of Freiburg
2011 Diploma thesis at the University of Alberta, Edmonton, Canada
2011 - present PhD student in the lab of Prof. Dr. Manfred Jung, Institute of Pharmaceutical Sciences, Albert-Ludwigs-University of Freiburg
2015 PhD thesis, Albert-Ludwigs-University of Freiburg

Awards, scholarships

A04 Chemical epigenetics: Inhibitors of methyl-lysine binding proteins

Methyl-lysine readers act as sensors of different histone methylation states and are mediators of epigenetic signalling. We already showed the importance of the reader protein Spindlin1 (Spin1) in oncogenic signalling. We will rationally optimise available inhibitors for Spin1 using structure-guided synthesis. We shall identify new chemotypes and chemical space as lead inhibitors for Spin1. Similar campaigns of assay development, screening, and compound optimisation will be carried out for other methyl-lysine readers.

Manfred Jung

1985 - 1989 Study of Pharmacy at the University of Marburg
1989 - 1990 Internship in a community pharmacy and at the University of Marburg
1990 - 1993 PhD work in Pharmaceutical Chemistry, University of Marburg
1993 - 1994 Postdoctoral fellow at the University of Ottawa, Canada
1994 - 2003 Group Leader, Department of Pharmaceutical and Medicinal Chemistry, University of Münster
2001 - 2003
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