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C07

Anna Köttgen

1994 - 2002 Studies of Human Medicine (M.D.), University of Freiburg
2005 - 2006 Master of Public Health (M.P.H.), Johns Hopkins Bloomberg School of Public Health, Baltimore, USA
2006 - 2008 Postdoctoral Research Fellow, The German Research Foundation, Dept. of Epidemiology, Johns Hopkins University, Baltimore, USA
2008 - 2009 Assistant Scientist, Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, USA

C07 Role of DNA methylation in human chronic kidney disease

Chronic kidney disease (CKD) is a complex disease affecting ~10% of adults and has a clear heritable component. Small cohort human and animal studies have linked altered DNA methylation to CKD. Therefore we will carry out epigenome-wide association studies (EWAS) of incident CKD and EWAS of CKD progression among patients with specific CKD aetiologies. This will be followed by integration of results with kidney cell-type specific gene expression and chromatin annotation maps and genome-wide DNA sequence variants.

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