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B06

Nicola Iovino

1997 - 2002 Study of Biology (BSc) and Master of Science in Biology (MSc), University of Naples Federico II, Italy
2002 - 2004 Researcher, Laboratory of Molecular Biology at Merck & Co. I.R.B.M., Rome, Italy
2004 - 2007 PhD visiting program at Rockefeller University, New York, USA
2007 - 2009 Postdoctoral training at Rockefeller University, New York, USA
and at LMU/Gene-Center, Munich
2009 - 2013

B06 Protamines removal, epigenetic inheritance and fertility

Fertilisation occurs when the two gametes fuse to produce a totipotent zygote. This process is characterised by intense chromatin remodelling of the paternal gamete including protamine eviction. The precise molecular mechanisms of paternal epigenome reprogramming and meiotic inheritance remain poorly understood. Using Drosophila as a model system, we will functionally dissect the epigenetic network controlling reprogramming of the paternal gamete during early embryogenesis.

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