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Josefina Castex

Institution: University Freiburg Medical Centre
Department: Dept. of Urology, Centre for Clinical Research
Phone: +49-(0)761-270 63260
Homepage: Roland Schüle

2005 - 2010 Bachelor in Dental Sc., Los Andes University, Chile
2011 - 2013 Master in Dental Sc. – Master in Biomedical Sc., KU Leuven, Belgium
2014 - 2017 PhD student in the Lab of Prof. Dr. Roland Schüle, Centre for Clinical Research, University Freiburg Medical Centre
2017 PhD thesis, Albert-Ludwigs-University of Freiburg


  • Castex J., Willmann D., Kanouni T., Arrigoni L., Li Y., Friedrich M., Schleicher M., Wohrle S., Pearson M., Kraut N., Meret M., Manke T., Metzger E., Schule R. and Gunther T. (2017) Inactivation of Lsd1 triggers senescence in trophoblast stem cells by induction of Sirt4. Cell Death Dis 8, e2631.
  • Fedorov O., Castex J., Tallant C., Owen D.R., Martin S., Aldeghi M., Monteiro O., Filippakopoulos P., Picaud S., Trzupek J.D., Gerstenberger B.S., Bountra C., Willmann D., Wells C., Philpott M., Rogers C., Biggin P.C., Brennan P.E., Bunnage M.E., Schule R., Gunther T., Knapp S. and Muller S. (2015) Selective targeting of the BRG/PB1 bromodomains impairs embryonic and trophoblast stem cell maintenance. Sci Adv 1, e1500723.